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BP and B-6

Goldenrod

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Blood pressure is a regular topic on this board and I was reading a few studies on pyridoxine and BP. B-6 is relatively cheap, I prefer the injectable form but one study uses the oral form:
https://www.ncbi.nlm.nih.gov/pubmed/8595083
Small sample size but interesting.

https://www.ncbi.nlm.nih.gov/pubmed/8723990
This study was on rats.

https://www.sciencedirect.com/science/article/abs/pii/S0306987799909556
This is simply a statement but appears he/she is trying to say b-6 may be helpful with dysphoria.

I’m not a doctor and just reading and passing information for the sake of sharing.
 

NG_F

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More than likely in Study #1 , The B6 is an essential co-factor which helps convert The amino acid L-Tyrosine into Dopamine, where if this enzymatic pathway is not efficient , the propensity for dietary tyrosine to convert to the catecholamines Norepinephrine and epinephrine( adrenaline) will be shifted in their favor.

The 3rd study illustrates the binding profile of B6 is quite a bit higher for GABA and Serotonin than Dopamine and Norepinephrine . Thus Dietary carbohydrate can help convert L-Tryptophan into > 5HTP> Serotonin via the decarboxylase enzyme.
Serotonin is inhibitory as is GABA, in the sense that it applies brakes to Dopamine and Nor-epi

Also B6 Lowers Prolactin which in turn lowers Systolic and Diastolic blood pressure via increased NOS production ( Nitric oxide Synthase)
It is the most potent vasodilator that our body can produce. Increased production can be brought about by combining L-Arginine with B6 . This will lead to enhanced Arterial Vasodilation.
 
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