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Human Chorionic Gonadotropin - HCG Mixing, Storage and Administration

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~Dr Juice~

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HCG MIXING, STORAGE, AND ADMINISTRATION




What is HCG?
Human Chorionic Gonadotropin (HCG) is a peptide hormone that mimics the action of luteinizing hormone (LH). LH is the hormone that stimulates the testes to produce testosterone.

When individuals take supplemental steroids their LH levels decline. The absence of an LH signal from the pituitary causes the testes to stop producing testosterone and can eventually cause testicular atrophy (shrinkage). Every individual will experience this differently but in some cases of prolonged steroid use the atrophy can be quite severe.

Based on research studies with healthy males and steroid use, 100iu HCG administered daily was enough to preserve full testicular function without causing desensitization or saturation associated with higher doses of HCG.

A convenient and more common alternative to the above recommendation would be 500iu twice a week. However, some research suggests it is more desirable to adhere to a lower more frequent dose of HCG to mimic the body’s natural LH release and minimize estrogen conversion.

Another popular HCG protocol is the end of cycle blast method. This can be used if you did not use HCG on cycle. This is often used towards the end of a cycle before PCT begins. Much higher doses are used, anywhere from 1000iu-5000iu. An example would be 2500iu to 5000iu. 2 to 3 times a week for 2 to 4 weeks.


What is HCG Concentration?
HCG comes in several concentrations. Some common examples are 1000iu, 2500iu, 5000iu and 10,000iu. The concentration of HCG should not be confused with volume because “iu” is an international measurement for concentration NOT volume. IU concentration should not be confused with mL, mg or cc’s.

No matter which concentration you decide to purchase once you mix the vial with a predetermined volume of sterile diluent the amount of HCG in your possession does not change. For example if you mix 5000iu HCG with 1mL of diluent you have 5000iu of HCG. If you took the same 5000iu HCG and mixed with 5mL of diluent you still only have 5000iu of HCG.


What is HCG Volume?
Now that we have a better understanding of HCG iu concentration let’s discuss dosing volume. This is where many people can get lost but trust me it is simple math. With a little effort and some experience it will become clear. While HCG concentration remains constant HCG’s measured volume changes. Measured volume is simply based on the amount of sterile diluent that the HCG was mixed with and the dosage amount that you wish to administer. Below you will see some simple examples of what reconstituted HCG concentrations will look like when combined with a specific amount of bac water.

Examples of HCG volume

  • HCG 10,000iu combined with 5mL of bac water - 5mL=10,000iu, 2.5mL=5,000iu, 1mL=2,000iu, .5mL=1,000iu

  • HCG 5,000iu combined with 5mL of bac water - 5mL=5,000iu, 1mL=1,000iu, .5mL=500iu

  • HCG 1,000iu combined with 1mL of bac water - 1mL=1,000iu, .5mL=500iu, .25mL=250iu



What do you mix HCG with?
For the purpose of this article the only thing that I recommend reconstituting HCG with is bacteriostatic water (bac water). Bacteriostatic water provides the longest HCG shelf life after constitution when stored properly.


How do you mix HCG?
Items needed: Bacteriostatic water, 3-5mL syringe, 25g 1/2” needle, and alcohol swabs.

Some HCG kits come with a sterile solution diluent. I do not recommend using the included diluent unless it is actual bacteriostatic water because the shelf life is only approximately 4-8 days with a simple sterile solution.

Your syringe size is not critical. I simply suggest that you use a syringe that allows you to mix the HCG with the appropriate amount of bac water in the minimal amount of diluent draws. Needle size is also not critical because bac water will draw easily in needles a small as 31g. I prefer 25g for speed of use and they are generally readily available at most drug stores such as Shoppers Drug Mart, Wal-Mart, Rexall, etc.

For the purpose of mixing instructions we will be mixing HCG 5,000iu with 5mL of bac water and we will assume your HCG and bac water are in 10mL vials. Here are our 16 steps to proper HCG mixing also called reconstituting;

1. Open the top on the bacteriostatic water vial.​
2. Use an alcohol swab to thoroughly sterilize the top of the vial and allow to air dry - DO NOT blow on it.​
3. Remove the 5mL syringe from the sterile packaging (if not using a syringe/needle combo install the needle).​
4. Uncap the needle.​
5. Pull back the plunger on the syringe to the 5mL mark plus a little more.​
6. Inject the air into the bac water.​
7. Draw 5mL of bac water from the vial.​
8. Place the cap back on the needle and set it aside.​
9. Open the top of the HCG vial.​
10. Use an alcohol swab to thoroughly sterilize the top of the HCG vial and allow to air dry - DO NOT blow on it.​
11. Remove the cap from the bac water syringe.​
12. Push the needle into the HCG vial.​
13. Place the HCG vial on its side - Horizontal to the ground.​
14. Slowly inject the bac water into the HCG vial allowing it to run down the side of the vial.​
15. Remove the needle from the vial, recap and properly discard.​
16. HCG generally will dissolve instantly but to ensure proper reconstitution slowly swirl the vial for 5-10 seconds. DO NOT shake.​


Following the above instructions you will now have 5000iu of HCG in 5mL of solution.


How do you Store Reconstituted HCG?
Reconstituted HCG should only be stored in the refrigerator to ensure proper shelf life and should immediately be placed back in the refrigerator after each use. When stored properly reconstituted HCG will remain effective for at least 25-30 days. Some articles state 6 weeks or longer.


How do you Administer HCG?
For ease of use and convenience I recommend administering HCG subcutaneously (sub-q) in the abdomen.

To perform a sub-q injection do a simple google or YouTube search. Here is a real quick one that you can reference;



What Size Needle and Syringe is Recommended?
I recommend a 1mL insulin syringe (slin pin) with a 25g - 30g 1/2” needle. You can use a needle length from 1/4” to 5/8” depending on the amount of abdominal fat that you have. 1/2” will work for 95% of the population.
 
Last edited:

rsacamano

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Excellent primer. Personally, I reconstitute every 4 weeks or so and have found a few things worth mentioning in addition to the excellent advice above. I've numbered for ease of seeing where they fit in the list above with some comments.

4.5) Insert drawing syringe into the vial with the hcg (powdered disk at the bottom) and draw the air from inside the vial

Doing step 4.5 removes air volume from the hcg vial equivalent to the incoming bacteriostatic water volume. Anyone who has not done this step, like me, has probably had the experience of watching the plunger of their insulin syringe shoot a foot or so in the aur when they added significant volume to the hcg vial (via the water volume) without first removing significant volume.

16) Don't swirl the vial. Place it between your hands and roll it back and forth slowly like cookie dough.

If you are injecting subq, use an insulin syringe. There is really no reason to use a larger pin. I am in the camp that feels hcg is an excellent compound and a cornerstone of hrt.
 
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Can I mix hcg 5000 with 2mL of bac water to get 2500iu/mL? I’ve never used hcg before, need help
 

Jdave

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Just want to add this about freezing HCG.
I’ve seen many places go back and forth about it and it CAN be done.
Why would you want to freeze it?
If you only have access to 5000 iu vials- and you’re using minimal doses on cycle you would need to have the whole 5000iu reconstituted- but wouldn’t be able to use it all in 4 week spans (28 days). Also it depends on if you use the 2x500iu /week method which I’ve seen but I’ve also seen 2x250iu/week. I’ve used both- both work fine. The former approach you’d be able to use the whole vial in 5 weeks then perhaps take week 6 or 6&7 off then start again for weeks 8 to 12 or 13. But the latter approach you’d require freezing.


I’ve frozen and thawed HCG twice- once Chinese generic and once Beyer pharma brand “Ovidac”. Both times I thawed the frozen left over HCG (thaw over night in fridge) and both times came up positive on a pregnancy test.
(A pregnancy test is a good way to make sure the HCG you have is still active... I’ve purchased generic HCG relabeled under a semi well known Canadian UGL- used it- noticed my nuts didn’t bounce back and tested it for it to come up “not pregnant” or rather there was not active HCG in the mix. Pregnant woman piss out HCG. I’m guessing the HCG was just old as shit or damaged - maybe faked idk)

I have read the vial you freeze it in should be wrapped in foil. No clue why- but that’s how I do it.
 
Last edited:

Bclint

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Hey thanks so much, but I couldn't help notice you gave instructions on HCG not HGH.
 

Bclint

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Just want to add this about freezing HCG.
I’ve seen many places go back and forth about it and it CAN be done.
Why would you want to freeze it?
If you only have access to 5000 iu vials- and you’re using minimal doses on cycle you would need to have the whole 5000iu reconstituted- but wouldn’t be able to use it all in 4 week spans (28 days). Also it depends on if you use the 2x500iu /week method which I’ve seen but I’ve also seen 2x250iu/week. I’ve used both- both work fine. The former approach you’d be able to use the whole vial in 5 weeks then perhaps take week 6 or 6&7 off then start again for weeks 8 to 12 or 13. But the latter approach you’d require freezing.


I’ve frozen and thawed HCG twice- once Chinese generic and once Beyer pharma brand “Ovidac”. Both times I thawed the frozen left over HCG (thaw over night in fridge) and both times came up positive on a pregnancy test.
(A pregnancy test is a good way to make sure the HCG you have is still active... I’ve purchased generic HCG relabeled under a semi well known Canadian UGL- used it- noticed my nuts didn’t bounce back and tested it for it to come up “not pregnant” or rather there was not active HCG in the mix. Pregnant woman piss out HCG. I’m guessing the HCG was just old as shit or damaged - maybe faked idk)

I have read the vial you freeze it in should be wrapped in foil. No clue why- but that’s how I do it.
I noticed that these are instructions for the use of HCG and not for Vitatrope HGH
 

MRX

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HCG keeps me horny!!
I get the same effect for several weeks then it tapers off
Do you find it to taper off (I'm assuming you're a trt cat but could be wrong lol)
My baseline libido is good but initial adding of HCG gives it a distinct bump
So I cycle it on and off for my prescribed trt: 2 on 2off
I'm ready to firs it up again actually
 
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