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Low paletes low whites

HungryMfkr

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Here's 2021 blood and 2019 (both unenhanced. 2021last cycle ended septembre).

Been working to improve some things, some worked some didn't. I've gone through multiple tests and they couldn't not find anything and just told me to monitor paletets and to not worry about it. (Next month)

(They checked organs by echo 2019) since then i've went to get a coloscopy since I had some history in the family and nothing to worry about.

Lkcs low 4 ( 4.5-10.8)
Plt low 129 (140-400) i've been lower at 123 and 126

Vpm high 13.3 (7.4-10.4)
#Neut low 1.8 (2.2-7.6)
Neut low 0.44 (0.50-0.70)
Lymp high 0.44 (0.17-0.42)

I do understand the relation between the low and high values stated as they correlate between themselves. My concern is that it seems that my body is fighting something for 3+ years any input suggestion to pinpoint the issue. I'm thinking about asking for a bone marrow biopsy just to clear things out. I was hoping to get things settled before next cycle.

I'm I over thinking this ?


(Bloodsheets from 2019 to 2021. The last sheet from second post relates the value stated)
 

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HungryMfkr

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Harley00

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Quick glance, i have to get to work, but looks like your fightimg an infection,or possible inflammation in the body.

Reason.. your ferritin in one of those labs were climbing to the high side. What was your iron at.
Maybe high hepcidin levels? Bone marrow wouldnt be a bad place to stsrt looking ither.

Ill look again later do you have any infections? Of any sort?

Any more labs? Ill look at all labs you have. Loke to see more to see a picture .
 

Harley00

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So, im thinkin.
- inflammation, or infection. Or..
- do you have high red blood cells by chance? Your hematocrit/hemoglobin is good, do you donate?

- iv just recently seen someones blood work where there wbc and platelets are low, and hematocrit/hemoglobin were good but there rbc were through the roof, or high.

Id be wondering what your iron and ferrtin are together, and tibc uibc and tran ferrtin.

Im wondering if your over producing on red blood cells due to and iron absorbtion issue of some kind causing, your platelets to drop and causing some type of inflammation making wbc drop, trying to scramble to fix issues.

That would be a direction id go in, the other issue is you may have blood clotting issues due to those numbers, have you looked into thrombocytopenia , i see your going in the direction of bone marrow, thats a good call for sure.(on that note though your calcium seems a bit low but noithing serious so i dunno)

You also could , like i mentioned up top may have some inflammation, and immune system issues, so looking at auto immune dieseses that trigger blood abnormalities in the immune system would be a good idea. That may be lowering the wbc count and effecting your blood markers. Everything is working overtime .

Your urine ph seems consistently high as well , thats something to watch for, you have alot of clues there, but a more full full complete blood test may help piece together other issues.

I would imagine your cortisol is taking a beating at these numbers trying to keep inflammation down, thats be another area.

Unfortunately thats all you provided so thats the best i got for advise.
 

HungryMfkr

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So, im thinkin.
- inflammation, or infection. Or..
- do you have high red blood cells by chance? Your hematocrit/hemoglobin is good, do you donate?

- iv just recently seen someones blood work where there wbc and platelets are low, and hematocrit/hemoglobin were good but there rbc were through the roof, or high.

Id be wondering what your iron and ferrtin are together, and tibc uibc and tran ferrtin.

Im wondering if your over producing on red blood cells due to and iron absorbtion issue of some kind causing, your platelets to drop and causing some type of inflammation making wbc drop, trying to scramble to fix issues.

That would be a direction id go in, the other issue is you may have blood clotting issues due to those numbers, have you looked into thrombocytopenia , i see your going in the direction of bone marrow, thats a good call for sure.(on that note though your calcium seems a bit low but noithing serious so i dunno)

You also could , like i mentioned up top may have some inflammation, and immune system issues, so looking at auto immune dieseses that trigger blood abnormalities in the immune system would be a good idea. That may be lowering the wbc count and effecting your blood markers. Everything is working overtime .

Your urine ph seems consistently high as well , thats something to watch for, you have alot of clues there, but a more full full complete blood test may help piece together other issues.

I would imagine your cortisol is taking a beating at these numbers trying to keep inflammation down, thats be another area.

Unfortunately thats all you provided so thats the best i got for advise.
Doc ordered the whole iron panel and the lab decided to do only ferritin as it wasn't justified enough ... (why labs got decisional liberty is beyond me)
(hb) are at 147 (134-165) in 2021. 161 in 2019 I tought this were the red cells marker ? No I never donated.

Ph is at 5 2021. From 8 2019 of course it is a daily value, i drasticly increased my water intake and limited my caffeine intake.

As far as other blood tests those are the most recent, I can do a request to obtain those that were done internally at the place they echo my organs in 2018-2019 but in their molind they didn't find anything so I didn't bother.

I'll definatively go back have a chat with the doc. I already asked to his nurse through email without an answer (when she provided the request to go back in a month with just checking plt and lkcs...)
for a more detail blood panel with the iron panel.

Thanks for the input i'll try and grab more info and a more in depht analysys, if you think of particular markers besides those stated that could be linked please let me know and i'll ask for them.
 

Harley00

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Doc ordered the whole iron panel and the lab decided to do only ferritin as it wasn't justified enough ... (why labs got decisional liberty is beyond me)
(hb) are at 147 (134-165) in 2021. 161 in 2019 I tought this were the red cells marker ? No I never donated.

Ph is at 5 2021. From 8 2019 of course it is a daily value, i drasticly increased my water intake and limited my caffeine intake.

As far as other blood tests those are the most recent, I can do a request to obtain those that were done internally at the place they echo my organs in 2018-2019 but in their molind they didn't find anything so I didn't bother.

I'll definatively go back have a chat with the doc. I already asked to his nurse through email without an answer (when she provided the request to go back in a month with just checking plt and lkcs...)
for a more detail blood panel with the iron panel.

Thanks for the input i'll try and grab more info and a more in depht analysys, if you think of particular markers besides those stated that could be linked please let me know and i'll ask for them.
No, red blood cells is RBC it is different then hemoglobin, hemoglobin is the protien thats inside red blood cells, it carries oxygen, i just seen a guy with good hemoglobin/hematocrit but high Rbc, with low platelets and low wbc. Red blood cells are made in your bone marrow, so if your over producing red blood cells, then that's an issue.

When doing labs, its very important to do all the labs at once, that way you get a clearer picture of whats going on.

If your ferritin was that high last year it could be higher now.

Full iron panel for sure
Iron
Tibc
Uibc
Trans ferritin
Ferritin
Full cbc again including RBC

Definitely wanna look at your blood clotting markers.

-D-Dimer
-Prothrombin

- esr
-Crp

Folate
B12

Too be honest, blood disorders are not my specialty, i do see inflammation, but the cause is unknown because we dont have a full picture of whats going on. Theres many more labs to do hear, you will have to ask your doctor to send you to a Hematologists, they would specialize in this.


Youll need to find out if you do have high RbC, and if you do then there could be an issue with lack of oxygen in your blood , or other blood abnormalities, maybe too much iron... maybe another issue, really not sure but if it were me id not ignore blood markers like this and make it an immediate priority, you dont wanna mess around with low wbc, or low platelets, because thats an important clotting marker. So if it were my guess something is depleting it, amd making it work overtime.

Pleass bring your info back, tag me or what ever im very intrested in these blood abnormalities, and the end result, so other can learn, my self included. Im more then willing to continue to go over labs with you when you get them as well.

Hopefully some of this helps.
 

BigBen

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Did they ultrasound your spleen? If it is enlarged, it can hoard platelets.
 

HungryMfkr

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Did they ultrasound your spleen? If it is enlarged, it can hoard platelets.
Yep they did, didn't find any abnormalities other than enlarged.
All they said afterwards was checking platelets levels every 6-12 months. With covid it was a pita so I didn't in 2020.
 
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Goldenrod

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Hi @HungryMfkr - are the labs being ordered and reviewed by a doctor? What does the doctor say?
I had lymphopenia for a few years (just low white lymphocytes) after getting sick. When I was sick they were 3 times the norm - clearly fighting something off. I was put through the paces by the medical system. After they couldn't determine what the issues were they sent me to an infectious disease specialist in another province.

Long story short, whatever it was - they never determined but the infectious disease specialist monitored me for 2 years. If you have an unknown infection, that is where I would start .
Good luck getting this sorted out.
 

HungryMfkr

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Hi @HungryMfkr - are the labs being ordered and reviewed by a doctor? What does the doctor say?
I had lymphopenia for a few years (just low white lymphocytes) after getting sick. When I was sick they were 3 times the norm - clearly fighting something off. I was put through the paces by the medical system. After they couldn't determine what the issues were they sent me to an infectious disease specialist in another province.

Long story short, whatever it was - they never determined but the infectious disease specialist monitored me for 2 years. If you have an unknown infection, that is where I would start .
Good luck getting this sorted out.
Yes it's half and half I go each year to see what's up exept covid 2020, basically i believe 3 years ago they sended me to do some more blood and scan the organs, didn't find anything and told me to not worry about it. To go get some blood every 6 months and check platelets levels. Now what I did is switched doc (went private) because the doc didn't want to give me the results besides everything is fine but your platelets...

So I asked and waiting for those old blood tests. The actual doc via his nurse is sending me back to see if lymp and plts are still low ... I ranted on how this was stupid running around in circles and asked for more bloods and to see a specialist to pinpoint the issue.

My first tought was maybe a cancer, so I went with family history and got a coloscopy, wich they remove a mass but it wasn't malign.

Then I tought I had multiple surgery so maybe a bacteria or something went into the bone marrow. So i'll ask for a biopsy they kinda make me feel like I'm just trippin but I really want to go at the bottom of this and wish to find out if this as anything to do with my chronic pains.

So in the end in your case did they suggested anything to do to raise the values to a normal state ?
 

Goldenrod

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Yes it's half and half I go each year to see what's up exept covid 2020, basically i believe 3 years ago they sended me to do some more blood and scan the organs, didn't find anything and told me to not worry about it. To go get some blood every 6 months and check platelets levels. Now what I did is switched doc (went private) because the doc didn't want to give me the results besides everything is fine but your platelets...

So I asked and waiting for those old blood tests. The actual doc via his nurse is sending me back to see if lymp and plts are still low ... I ranted on how this was stupid running around in circles and asked for more bloods and to see a specialist to pinpoint the issue.

My first tought was maybe a cancer, so I went with family history and got a coloscopy, wich they remove a mass but it wasn't malign.

Then I tought I had multiple surgery so maybe a bacteria or something went into the bone marrow. So i'll ask for a biopsy they kinda make me feel like I'm just trippin but I really want to go at the bottom of this and wish to find out if this as anything to do with my chronic pains.

So in the end in your case did they suggested anything to do to raise the values to a normal state ?
No, the only time my lymphocytes have been in the normal range is when I am am taking low dose Primo with my TRT. Might sound weird but for whatever reason - multiple blood tests show this. My numbers are just below norm, similar to yours but none of the doctors were worried about it except the infectious disease doc who wanted to explore because the trigger was my lymphocytes 3-4 times the norm when I felt like crap which led him to believe it started with a viral or bacterial infection. The end result was after seeing a GP, internal medicine specialist, 2 neurologists - had nervous system symptoms, and finally an infectious disease specialist. The end diagnosis was an unknown virus that attacked my nervous system. That was a guess but they rules everything out.
Told to keep doing what I was doing - eating healthy, exercises as much as I could (I was still feeling like shit), and live my life. This was a very long time ago and it eventually just went away but my lymphocytes never went back to the normal range.
 

HungryMfkr

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No, the only time my lymphocytes have been in the normal range is when I am am taking low dose Primo with my TRT. Might sound weird but for whatever reason - multiple blood tests show this. My numbers are just below norm, similar to yours but none of the doctors were worried about it except the infectious disease doc who wanted to explore because the trigger was my lymphocytes 3-4 times the norm when I felt like crap which led him to believe it started with a viral or bacterial infection. The end result was after seeing a GP, internal medicine specialist, 2 neurologists - had nervous system symptoms, and finally an infectious disease specialist. The end diagnosis was an unknown virus that attacked my nervous system. That was a guess but they rules everything out.
Told to keep doing what I was doing - eating healthy, exercises as much as I could (I was still feeling like shit), and live my life. This was a very long time ago and it eventually just went away but my lymphocytes never went back to the normal range.
Thanks for that, I'm literally waiting to clear this out before doing primo and I didn't want to add aas doing blood to messed up the readings. I talked to the nurse yesterday and after checking levels if they are still what they are the doc will send me see an hematologist so I guess I'll cycle this winter lol
 

Goldenrod

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Thanks for that, I'm literally waiting to clear this out before doing primo and I didn't want to add aas doing blood to messed up the readings. I talked to the nurse yesterday and after checking levels if they are still what they are the doc will send me see an hematologist so I guess I'll cycle this winter lol
I wasn't suggesting taking Primo to get your cell count up, I was just pleasantly surprised when I added Primo and my lymphocyte count went into the normal range.
Hopefully you get this sorted out. You mentioned chronic pain - is it your whole body or chronic injuries that won't heal?
 

HungryMfkr

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I wasn't suggesting taking Primo to get your cell count up, I was just pleasantly surprised when I added Primo and my lymphocyte count went into the normal range.
Hopefully you get this sorted out. You mentioned chronic pain - is it your whole body or chronic injuries that won't heal?
I wasn’t seeing it as a fix. I made a thread couple weeks ago about, primo & low deca as it was the route I wanted to go. Still believe that in my situation it could be more than benefical.

I really tough my blood were going to be optimal. Simply didn't want to add any compound to mess up the investigation.

Long story short, Chronic pain is in lower back and hips.
Both were injuried. l5-s1 is soldered so l4-l5 act as the hinge but the disc is shrinked/hypoplasia with some osteoarthritis in the facets and vertabrea. So not much of a fix and live with it. L2-l3 herniated (seems under control) Had multiple cortisone infiltration in the past as well as a radiofrequency ablation whom both gave fuck all. With all the usual rehab and more. Hips one had surgery fractured acetabulum, labral tear and femoral head resurfacing. Never came back. Anything that cause trouble more than 6 months is labeled as chronic pain 🤷‍♂️ once you go through surgery and have problems in my experience when you come up to another doc you're like a hot potato that no ones want.

The best treatment in the last decade as been no meds, keep moving and build muscle around to keep everything working. On aas pain is mitigated by a lot. Time flies, couple years ago I stopped all meds because I felt like shit and was tired of it, transitionned to thc and cbd wich did his thing a while. Then like the pills it would always take more and you get to a point were it messes with everything else. So threw that away for an extented period, I really tought it might of triggered an immune response and might of been the cause of low platelets, etc for some reason but it's not.

As you stated we might never know, it's simply a relief to know if there's a concern to get rid of.
 
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